Neuropeptide FF

For research use only. Not for therapeutic Use.

  • CAT Number: P000205
  • CAS Number: 99566-27-5
  • Molecular Formula: C54H76N14O10
  • Molecular Weight: 1081.29
  • Purity: ≥95%
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Endogenous antiopioid peptide and agonist at NPFF<sub>1</sub> and NPFF<sub>2</sub> receptors (K<sub>i</sub> values are 2.82 and 0.21 nM respectively). Exhibits anorexigenic effects following i.c.v. administration.


Catalog Number P000205
CAS Number 99566-27-5
Molecular Formula C54H76N14O10
Purity ≥95%
Target Neuropeptide FF Receptor
Solubility Soluble to 0.50 mg/ml in water
Storage Desiccate at -20C
IUPAC Name (2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
InChI InChI=1S/C54H76N14O10/c1-32(2)28-41(66-47(72)36(55)29-33-14-6-3-7-15-33)50(75)67-42(31-35-18-10-5-11-19-35)51(76)64-39(23-25-45(57)70)53(78)68-27-13-21-43(68)52(77)63-38(22-24-44(56)69)49(74)62-37(20-12-26-61-54(59)60)48(73)65-40(46(58)71)30-34-16-8-4-9-17-34/h3-11,14-19,32,36-43H,12-13,20-31,55H2,1-2H3,(H2,56,69)(H2,57,70)(H2,58,71)(H,62,74)(H,63,77)(H,64,76)(H,65,73)(H,66,72)(H,67,75)(H4,59,60,61)/t36-,37-,38-,39-,40-,41-,42-,43-/m0/s1
InChIKey HWYCFZUSOBOBIN-AQJXLSMYSA-N
SMILES CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCC(=O)N)C(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=CC=C4)N

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