For research use only. Not for therapeutic Use.
Nevadensin（Cat No.:M124001） is a natural compound that acts as a selective inhibitor of human carboxylesterase 1 (hCE1) with an IC50 value of 2.64 μM. It possesses a range of pharmacological effects, including anti-mycobacterium tuberculosis, antitussive, anti-inflammatory, and anti-hypertensive properties. Nevadensin’s inhibition of hCE1 activity may contribute to its diverse pharmacological activities. Further research is necessary to explore its mechanisms of action and potential therapeutic applications in treating tuberculosis, cough, inflammation, and hypertension.
| Catalog Number | M124001 |
| CAS Number | 10176-66-6 |
| Molecular Formula | C18H16O7 |
| Purity | ≥95% |
| Storage | 4°C, protect from light |
| IUPAC Name | 5,7-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)chromen-4-one |
| InChI | InChI=1S/C18H16O7/c1-22-10-6-4-9(5-7-10)12-8-11(19)13-14(20)17(23-2)15(21)18(24-3)16(13)25-12/h4-8,20-21H,1-3H3 |
| InChIKey | KRFBMPVGAYGGJE-UHFFFAOYSA-N |
| SMILES | COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3O)OC)O)OC |
