Nevirapine

• CAT Number: A000432
• CAS Number: 129618-40-2
• Molecular Formula: C15H14N4O
• Molecular Weight: 266.30
• Purity: ≥95%
• Synonyms: 129618-40-2; Viramune; BI-RG-587; Viramune XR; BIRG 0587
• Target: HIV
• Solubility: >13.3mg/mL in DMSO
• Storage: -20°C
• IUPAC Name: 2-cyclopropyl-7-methyl-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
• InChI: InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)
• InChIKey: NQDJXKOVJZTUJA-UHFFFAOYSA-N
• SMILES: CC1=C2C(=NC=C1)N(C3=C(C=CC=N3)C(=O)N2)C4CC4

Nevirapine（Cat No.:A000432）is a high-purity non-nucleoside reverse transcriptase inhibitor (NNRTI) widely used in HIV research. It targets the HIV-1 reverse transcriptase enzyme by binding to an allosteric site, disrupting viral DNA synthesis and replication. Nevirapine is pivotal in studying antiretroviral therapy mechanisms, resistance patterns, and combination treatments. Known for its oral bioavailability and effectiveness, it is extensively used in exploring strategies to prevent mother-to-child HIV transmission. Its stability and efficacy make it a valuable tool for advancing HIV treatment research and developing innovative therapeutic approaches.

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