For research use only. Not for therapeutic Use.
NG52（Cat No.:I002638）is a novel investigational compound known for its selective inhibition of specific kinases involved in cellular signaling pathways related to cancer progression. It demonstrates potent anti-proliferative effects against various tumor cell lines, making it a promising candidate in cancer therapeutics. By targeting key enzymes, NG52 disrupts critical processes such as cell cycle progression and apoptosis, leading to reduced tumor growth. Ongoing studies are focused on elucidating its pharmacokinetic properties and optimizing dosing regimens, with the aim of enhancing its efficacy in combination with other anticancer agents for improved treatment outcomes.
| Catalog Number | I002638 |
| CAS Number | 212779-48-1 |
| Synonyms | Compound 52 |
| Molecular Formula | C₁₆H₁₉ClN₆O |
| Purity | ≥95% |
| Target | Cdc28p |
| Solubility | DMSO 200 mg/ml |
| Storage | 2-8°C |
| IC50 | 7 uM |
| IUPAC Name | 2-[[6-(3-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]ethanol |
| InChI | InChI=1S/C16H19ClN6O/c1-10(2)23-9-19-13-14(20-12-5-3-4-11(17)8-12)21-16(18-6-7-24)22-15(13)23/h3-5,8-10,24H,6-7H2,1-2H3,(H2,18,20,21,22) |
| InChIKey | XZEFMZCNXDQXOZ-UHFFFAOYSA-N |
| SMILES | CC(C)N1C=NC2=C(N=C(N=C21)NCCO)NC3=CC(=CC=C3)Cl |
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