For research use only. Not for therapeutic Use.
NH125 (Cat No.:I010765) is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, its selectivity is 125 times higher than that of PKC, PKA, and CaMKII, and it is also a potent histidine kinase inhibitor.NH125 Reduces the blood pressure of SHR and reduces the production of ROS and induced inflammatory molecules, and reduces the hypertrophy of SHR’s superior mesenteric artery.
Catalog Number | I010765 |
CAS Number | 278603-08-0 |
Synonyms | 1-Hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazolium iodide |
Molecular Formula | C27H45IN2 |
Purity | ≥95% |
Solubility | Soluble to 100 mM in DMSO and to 75 mM in ethanol |
Storage | -20°C |
IUPAC Name | 1-benzyl-3-hexadecyl-2-methylimidazol-1-ium;iodide |
InChI | InChI=1S/C27H45N2.HI/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-28-23-24-29(26(28)2)25-27-20-17-16-18-21-27;/h16-18,20-21,23-24H,3-15,19,22,25H2,1-2H3;1H/q+1;/p-1 |
InChIKey | RVWOHCBHAGBLLT-UHFFFAOYSA-M |
SMILES | CCCCCCCCCCCCCCCCN1C=C[N+](=C1C)CC2=CC=CC=C2.[I-] |