For research use only. Not for therapeutic Use.
NH125 (Cat No.:I010765) is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, its selectivity is 125 times higher than that of PKC, PKA, and CaMKII, and it is also a potent histidine kinase inhibitor.NH125 Reduces the blood pressure of SHR and reduces the production of ROS and induced inflammatory molecules, and reduces the hypertrophy of SHR’s superior mesenteric artery.
| Catalog Number | I010765 |
| CAS Number | 278603-08-0 |
| Synonyms | 1-Hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazolium iodide |
| Molecular Formula | C27H45IN2 |
| Purity | ≥95% |
| Target | Autophagy |
| Solubility | Soluble to 100 mM in DMSO and to 75 mM in ethanol |
| Storage | -20°C |
| IUPAC Name | 1-benzyl-3-hexadecyl-2-methylimidazol-1-ium;iodide |
| InChI | InChI=1S/C27H45N2.HI/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-28-23-24-29(26(28)2)25-27-20-17-16-18-21-27;/h16-18,20-21,23-24H,3-15,19,22,25H2,1-2H3;1H/q+1;/p-1 |
| InChIKey | RVWOHCBHAGBLLT-UHFFFAOYSA-M |
| SMILES | CCCCCCCCCCCCCCCCN1C=C[N+](=C1C)CC2=CC=CC=C2.[I-] |
