For research use only. Not for therapeutic Use.
NHS-SS-Ph is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
| Catalog Number | I043434 |
| CAS Number | 2750799-12-1 |
| Synonyms | 2-[2-(2,5-dioxopyrrolidin-1-yl)oxycarbonyloxyethyldisulfanyl]ethyl benzoate |
| Molecular Formula | C16H17NO7S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C16H17NO7S2/c18-13-6-7-14(19)17(13)24-16(21)23-9-11-26-25-10-8-22-15(20)12-4-2-1-3-5-12/h1-5H,6-11H2 |
| InChIKey | VCMZIGLIZQEWHS-UHFFFAOYSA-N |
| SMILES | C1CC(=O)N(C1=O)OC(=O)OCCSSCCOC(=O)C2=CC=CC=C2 |
| Reference | [1]. Ali Gilles Tchenguise MISEREZ, et al. Isolated peptide for a peptide coacervate, and methods of use thereof. WO2021246961A1. |
