For research use only. Not for therapeutic Use.
NIAD-4 is a fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM[1].
| Catalog Number | R065807 |
| CAS Number | 868592-56-7 |
| Synonyms | 2-[[5-[5-(4-hydroxyphenyl)thiophen-2-yl]thiophen-2-yl]methylidene]propanedinitrile |
| Molecular Formula | C18H10N2OS2 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H10N2OS2/c19-10-12(11-20)9-15-5-6-17(22-15)18-8-7-16(23-18)13-1-3-14(21)4-2-13/h1-9,21H |
| InChIKey | KLFRZDOQQDHVSS-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C2=CC=C(S2)C3=CC=C(S3)C=C(C#N)C#N)O |
| Reference | [1]. Kenneth T. Cheng, et al. [[5′-(4-Hydroxyphenyl)[2,2’-bithiophen]-5-yl]methylene]-propanedinitrile NIAD-4. |
