For research use only. Not for therapeutic Use.
<p style=/line-height:25px/>NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional).<br>IC50 value: 16/11 nM(Binding/Functional IC50) [1]<br>Target: EBI2/GPR183 antagonist<br>NIBR189 is a potent and selective EBI2 antagonist with improved pharmacokinetic properties which will help to probe the physiological function of EBI2 in health and disease.<br></p>
| Catalog Number | I002030 |
| CAS Number | 1599432-08-2 |
| Synonyms | (E)-3-(4-bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one |
| Molecular Formula | C21H21BrN2O3 |
| Purity | ≥95% |
| Target | GPCR/G Protein |
| Solubility | DMSO: ≥ 47 mg/mL |
| Storage | Desiccate at -20C |
| IC50 | 16/11 nM(Binding/Functional IC50) [1] |
| InChIKey | OFHXXBRBGWUOHR-NYYWCZLTSA-N |
| Reference | <p style=/line-height:25px/> |
