For research use only. Not for therapeutic Use.
NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity[1].
| Catalog Number | I018991 |
| CAS Number | 494830-67-0 |
| Molecular Formula | C₂₆H₃₆N₂O₄ |
| Purity | ≥95% |
| Reference | [1]. Wang X, et al. Identification of a small-molecule compound that inhibits homodimerization of oncogenic NAC1 protein and sensitizes cancer cells to anticancer agents. J Biol Chem. 2019 May 17. pii: jbc.RA119.007664. |
