Nicardipine-d3 hydrochloride

• CAT Number: S000287
• CAS Number: 1432061-50-1
• Molecular Formula: C26H27D3ClN3O6
• Molecular Weight: 519.00
• Purity: ≥95%
• Target: Neuronal Signaling
• IUPAC Name: 5-O-[2-[benzyl(trideuteriomethyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride
• InChI: InChI=1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H/i3D3
• InChIKey: AIKVCUNQWYTVTO-FJCVKDQNSA-N
• SMILES: CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC.Cl

Nicardipine-d3 hydrochloride（Cat No.:S000287） is a deuterated version of nicardipine hydrochloride, where three hydrogen atoms are replaced with deuterium, improving its molecular stability. This enhancement makes it an excellent internal standard for analytical techniques like mass spectrometry and NMR spectroscopy. Nicardipine is a calcium channel blocker used to treat hypertension and to manage angina. By incorporating deuterium, nicardipine-d3 hydrochloride facilitates more precise pharmacokinetic and metabolic research, providing clearer insights into the drug’s absorption, distribution, metabolism, and elimination, thereby improving our understanding of its therapeutic effects and safety profile.