For research use only. Not for therapeutic Use.
Nicomol is an orally active hypolipidemic agent that can increase the high density lipoprotein cholesterol (HDL-C) level. Nicomol inhibits the rapid rise of plasma free fatty acids[1][2].
Catalog Number | I033268 |
CAS Number | 27959-26-8 |
Synonyms | [2-hydroxy-1,3,3-tris(pyridine-3-carbonyloxymethyl)cyclohexyl]methyl pyridine-3-carboxylate |
Molecular Formula | C34H32N4O9 |
Purity | ≥95% |
InChI | InChI=1S/C34H32N4O9/c39-28(24-6-1-12-35-16-24)44-20-33(21-45-29(40)25-7-2-13-36-17-25)10-5-11-34(32(33)43,22-46-30(41)26-8-3-14-37-18-26)23-47-31(42)27-9-4-15-38-19-27/h1-4,6-9,12-19,32,43H,5,10-11,20-23H2 |
InChIKey | VRAHPESAMYMDQI-UHFFFAOYSA-N |
SMILES | C1CC(C(C(C1)(COC(=O)C2=CN=CC=C2)COC(=O)C3=CN=CC=C3)O)(COC(=O)C4=CN=CC=C4)COC(=O)C5=CN=CC=C5 |
Reference | [1]. N Yamazaki, et al. Arrhythmogenic effects of acute free fatty acid mobilization on ischemic heart. Recent Adv Stud Cardiac Struct Metab. 1976 May 26-29;12:271-7. [2]. S Ikeda, et al. Effect of nicomol on high density lipoprotein (HDL) subfractions, HDL2e and HDL3e, separated by electrophoresis. Acta Med Okayama. 1981 Apr;35(2):143-8. |