For research use only. Not for therapeutic Use.
Nifurpirinol (P-7138) is a nitroaromatic antibiotic and acts as a novel substrate for the bacterial nitroreductase (NTR) enzyme. Nifurpirinol is a more potent proagent compared to Metronidazole to trigger cell-ablation in nitroreductase expressing transgenic models[1].
| Catalog Number | M055125 |
| CAS Number | 13411-16-0 |
| Synonyms | [6-[(E)-2-(5-nitrofuran-2-yl)ethenyl]pyridin-2-yl]methanol |
| Molecular Formula | C12H10N2O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C12H10N2O4/c15-8-10-3-1-2-9(13-10)4-5-11-6-7-12(18-11)14(16)17/h1-7,15H,8H2/b5-4+ |
| InChIKey | JQKHJQJVKRFMCO-SNAWJCMRSA-N |
| SMILES | C1=CC(=NC(=C1)C=CC2=CC=C(O2)[N+](=O)[O-])CO |
| Reference | [1]. David Bergemann, et al. Nifurpirinol: A more potent and reliable substrate compared to metronidazole for nitroreductase-mediated cell ablations. Wound Repair Regen |
