For research use only. Not for therapeutic Use.
Nigranoic Acid（Cat No.:I017629）is a high-purity triterpenoid compound derived from Schisandra species, widely used in pharmacological and natural product research. Known for its potent anti-inflammatory, hepatoprotective, and anticancer activities, it is instrumental in exploring therapeutic strategies for liver diseases, cancer, and inflammation-related disorders. Nigranoic Acid is also studied for its ability to modulate signaling pathways and protect against oxidative stress. Its unique bioactivity and stability make it a valuable tool for investigating natural product mechanisms and developing innovative treatments.
| Catalog Number | I017629 |
| CAS Number | 39111-07-4 |
| Molecular Formula | C₃₀H₄₆O₄ |
| Purity | ≥95% |
| Target | HIV |
| IUPAC Name | (Z,6R)-6-[(1S,4R,5R,8S,9S,12S,13R)-13-(2-carboxyethyl)-4,8-dimethyl-12-prop-1-en-2-yl-5-tetracyclo[7.5.0.01,13.04,8]tetradecanyl]-2-methylhept-2-enoic acid |
| InChI | InChI=1S/C30H46O4/c1-19(2)22-10-11-24-28(6)14-12-23(20(3)8-7-9-21(4)26(33)34)27(28,5)16-17-30(24)18-29(22,30)15-13-25(31)32/h9,20,22-24H,1,7-8,10-18H2,2-6H3,(H,31,32)(H,33,34)/b21-9-/t20-,22+,23-,24+,27-,28+,29-,30+/m1/s1 |
| InChIKey | NJFOSFIPGRXARF-BRTULJEKSA-N |
| SMILES | C[C@H](CC/C=C(/C)\C(=O)O)[C@H]1CC[C@@]2([C@@]1(CC[C@]34[C@H]2CC[C@H]([C@]3(C4)CCC(=O)O)C(=C)C)C)C |
| Reference | [1]. Sun HD, et al. Nigranoic acid, a triterpenoid from Schisandra sphaerandra that inhibits HIV-1 reverse transcriptase. J Nat Prod. 1996 May;59(5):525-7.<br>[2]. Feng T, et al. Protective effects of nigranoic acid on cerebral ischemia-reperfusion injury and its mechanism involving apoptotic signaling pathway. Cell Biochem Biophys. 2015 Jan;71(1):345-51. |
