Nilotinib hydrochloride

• CAT Number: I047380
• CAS Number: 923288-95-3
• Molecular Formula: C28H22F3N7O.HCl
• Molecular Weight: 565.98
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.Cl

Nilotinib hydrochloride (AMN-107) is the hydrochloride salt form of nilotinib, an orally bioavailable Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity.

Reference

[1] Weisberg E, et al. Blood. 2007, 109(5):2112-20.