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NITRARINE Di-HCl(cas 20069-05-0) is a hypotensive, a spasmolytic, a coronary dilator and a sedative in experimental arrhythmias.
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Alkaloid<!–C<sub>20</sub>H<sub>25</sub>N<sub>3</sub>.2HCl–>, from plants of the Zygophyllaceae family<br />
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In experimental arrhythmias in the cat, caused by calcium chloride, <strong>Aconitine </strong>and electric cardiac stimulation, <strong>Nitrarine</strong> <strong>dihydrochloride </strong>presents a hypotensive, spasmolytic, coronary dilating and sedative action. Its antiarrhythmic properties are due to its stabilizating effects on the membrane and its coronary dilating action. <strong>Nitrarine dihydrochloride</strong> is 3-4 times as potent as <strong>Novocainamide </strong>and <strong>Quinidine</strong>, and the duration of its effect is 2-5 times longer than that of these products.
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Catalog Number | T000089 |
CAS Number | 20069-05-0 |
Molecular Formula | C20H25N3.2HCl |
Purity | ≥95% |
Solubility | Well in water, methanol and ethanol |
Storage | Store at +4 °C, in dark place. |
Reference | – Nasirov et al. Chem. Nat. Comp. (1976). 3:334-345<br /> |