For research use only. Not for therapeutic Use.
Nivalenol(Cat No.:R037075)is a type B trichothecene mycotoxin produced by fungi, particularly Fusarium species, which can contaminate crops like wheat, barley, and corn. It is known for its potent toxicity, affecting both humans and animals upon ingestion. Nivalenol inhibits protein synthesis by binding to ribosomes, leading to cell damage and immune suppression. It is associated with a range of health effects, including nausea, vomiting, and diarrhea, as well as long-term risks such as carcinogenicity. Nivalenol contamination in food is a significant concern, and monitoring is essential to reduce exposure in agricultural products.
Catalog Number | R037075 |
CAS Number | 23282-20-4 |
Synonyms | (3α,4β,7α)-12,13-Epoxy-3,4,7,15-tetrahydroxytrichothec-9-en-8-one; 12,13-Epoxy-3α,4β,7α,15-tetrahydroxytrichothec-9-en-8-one;?3α,4β,7α,15-Tetrahydroxyscrip-9-en-8-one; NSC 269143; |
Molecular Formula | C15H20O7 |
Purity | ≥95% |
Target | Anti-infection |
Storage | -20°C |
IUPAC Name | (1S,2R,3S,7R,9R,10R,11S,12S)-3,10,11-trihydroxy-2-(hydroxymethyl)-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-one |
InChI | InChI=1S/C15H20O7/c1-6-3-7-14(4-16,11(20)8(6)17)13(2)10(19)9(18)12(22-7)15(13)5-21-15/h3,7,9-12,16,18-20H,4-5H2,1-2H3/t7-,9-,10-,11-,12-,13-,14-,15+/m1/s1 |
InChIKey | UKOTXHQERFPCBU-XBXCNEFVSA-N |
SMILES | CC1=C[C@@H]2[C@]([C@@H](C1=O)O)([C@]3([C@@H]([C@H]([C@H]([C@@]34CO4)O2)O)O)C)CO |