Nizatidine-d3

• CAT Number: R013111
• CAS Number: 1246833-99-7
• Molecular Formula: C12H21N5O2S2
• Molecular Weight: 334.471
• Purity: ≥95%
• Synonyms: N-[2-[[[2-[(Dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N’-(methyl-d3)-2-nitro-1,1-ethenediamine; LY-139037-d3; ZE-101-d3; ZL-101-d3; Axid-d3; Calmaxid-d3; Cronizat-d3; Distaxid-d3; Gastrax-d3; Nizax-d3; Nizaxid-d3
• Target: Neuronal Signaling
• Storage: Store at RT
• IUPAC Name: (E)-1-N-[2-[[2-[(dimethylamino)methyl]-1,3-thiazol-4-yl]methylsulfanyl]ethyl]-2-nitro-1-N/'-(trideuteriomethyl)ethene-1,1-diamine
• InChI: InChI=1S/C12H21N5O2S2/c1-13-11(6-17(18)19)14-4-5-20-8-10-9-21-12(15-10)7-16(2)3/h6,9,13-14H,4-5,7-8H2,1-3H3/b11-6+/i1D3
• InChIKey: SGXXNSQHWDMGGP-OFYUJABRSA-N
• SMILES: [2H]C([2H])([2H])N/C(=C\[N+](=O)[O-])/NCCSCC1=CSC(=N1)CN(C)C

Nizatidine-d3 is a deuterated form of nizatidine, an H2 receptor antagonist commonly used to treat conditions like ulcers and gastroesophageal reflux disease (GERD). This compound features three deuterium atoms, which enhance the stability and allow for precise analysis in pharmacokinetic and metabolic studies using mass spectrometry. Nizatidine-d3 is particularly valuable in pharmaceutical research for investigating the drug’s absorption, distribution, metabolism, and excretion (ADME) properties. The deuterium labeling ensures accurate tracking in biological systems, making it an essential tool in the development of safer and more effective therapies for acid-related disorders.