For research use only. Not for therapeutic Use.
NK1 receptor antagonist 2 is a NK1 receptor antagonist. NK1 receptor antagonist 2 can be used for the research of tinnitus and hearing loss[1].
| Catalog Number | I042321 |
| CAS Number | 579475-17-5 |
| Synonyms | (2R,4R)-4-[(8aS)-6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl]-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide |
| Molecular Formula | C31H35F7N4O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C31H35F7N4O2/c1-18-12-23(32)4-6-26(18)27-16-24(40-10-11-41-25(17-40)5-7-28(41)43)8-9-42(27)29(44)39(3)19(2)20-13-21(30(33,34)35)15-22(14-20)31(36,37)38/h4,6,12-15,19,24-25,27H,5,7-11,16-17H2,1-3H3/t19-,24-,25+,27-/m1/s1 |
| InChIKey | XWNBGDJPEXZSQM-QSEFLHEVSA-N |
| SMILES | CC1=C(C=CC(=C1)F)C2CC(CCN2C(=O)N(C)C(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4CCN5C(C4)CCC5=O |
| Reference | [1]. Soren Rahn Christensen, et al. Composition comprising an nk-1 receptor antagonist and an ssri for the treatment of tinnitus and hearing loss. Patent. WO2008046882 A2 |
