For research use only. Not for therapeutic Use.
NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases[1].
NLRP3-IN-11 has biological activity with an IC50 value of <0.3 μM in human PBMC NLRP3 assay[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
NLRP3-IN-11 Related Antibodies
| Catalog Number | I042754 |
| CAS Number | 2769040-91-5 |
| Synonyms | 5-chloro-2-[4-[(2-hydroxy-2-methylpropyl)amino]pyrido[3,4-d]pyridazin-1-yl]phenol |
| Molecular Formula | C17H17ClN4O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C17H17ClN4O2/c1-17(2,24)9-20-16-13-8-19-6-5-11(13)15(21-22-16)12-4-3-10(18)7-14(12)23/h3-8,23-24H,9H2,1-2H3,(H,20,22) |
| InChIKey | UDNICEVHCYUJFU-UHFFFAOYSA-N |
| SMILES | CC(C)(CNC1=NN=C(C2=C1C=NC=C2)C3=C(C=C(C=C3)Cl)O)O |
| Reference | [1]. HY-W048205, et al. Compounds for inhibiting NLRP3 and uses thereof. Patent. US11319319B1. |
