For research use only. Not for therapeutic Use.
NLRP3-IN-17（Cat No.:I041169）is a selective small molecule inhibitor designed to target the NLRP3 inflammasome, a key player in the body’s inflammatory response. By inhibiting NLRP3, this compound aims to reduce the production of pro-inflammatory cytokines, which are involved in various autoimmune and inflammatory diseases. NLRP3-IN-17 shows promise in preclinical studies for treating conditions such as rheumatoid arthritis, gout, and other inflammatory disorders. Researchers are currently conducting clinical trials to evaluate its safety, efficacy, and potential as a novel treatment for diseases driven by excessive inflammation.
| CAS Number | 2254432-75-0 |
| Synonyms | 1-[N-cyano-S-(4-methylphenyl)sulfonimidoyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea |
| Molecular Formula | C21H22N4O2S |
| Purity | ≥95% |
| IUPAC Name | 1-[N-cyano-S-(4-methylphenyl)sulfonimidoyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea |
| InChI | InChI=1S/C21H22N4O2S/c1-14-8-10-17(11-9-14)28(27,23-13-22)25-21(26)24-20-18-6-2-4-15(18)12-16-5-3-7-19(16)20/h8-12H,2-7H2,1H3,(H2,23,24,25,26,27) |
| InChIKey | SOZVZFKPLUXVMT-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)S(=NC#N)(=O)NC(=O)NC2=C3CCCC3=CC4=C2CCC4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
