N,N’-Methylenebis(acrylamide)

For research use only. Not for therapeutic Use.

  • CAT Number: R029890
  • CAS Number: 110-26-9
  • Molecular Formula: C7H10N2O2
  • Molecular Weight: 154.169
  • Purity: ≥95%
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N,N’-Methylenebis(acrylamide) (CAT: R029890) is a versatile chemical compound widely used in laboratory applications, especially in gel electrophoresis techniques. This white crystalline powder possesses a neutral odor. It plays a crucial role in gel preparation by acting as a cross-linking agent. When polymerized with acrylamide, it forms cross-links within the resulting polyacrylamide gel matrix. These cross-links create a network structure that enhances the stability and firmness of the gel. This property is particularly valuable in gel electrophoresis, where the gel matrix provides a medium for separating biomolecules based on size and charge.


Catalog Number R029890
CAS Number 110-26-9
Synonyms

Bisacrylamide; MBA; MBAA; Methylenebisacrylamide; Methylenediacrylamide; N,N’-Diacryloylmethylenediamine; N,N’-Methylenebis(2-propenamide); N,N’-Methylenebis(acrylamide); N,N’-Methylenediacrylamide; NMBA; NSC 406836; NSC 7774; Triam 507

Molecular Formula C7H10N2O2
Purity ≥95%
Storage Store at -20°C
IUPAC Name N-[(prop-2-enoylamino)methyl]prop-2-enamide
InChI InChI=1S/C7H10N2O2/c1-3-6(10)8-5-9-7(11)4-2/h3-4H,1-2,5H2,(H,8,10)(H,9,11)
InChIKey ZIUHHBKFKCYYJD-UHFFFAOYSA-N
SMILES C=CC(=O)NCNC(=O)C=C
Reference

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<span style=”font-size:12px;”>1. J Chromatogr A. 2006 May 12;1114(2):239-49. doi: 10.1016/j.chroma.2006.02.033. Epub 2006 Mar 10.Temperature sensitive dopamine-imprinted (N,N-methylene-bis-acrylamide cross-linked) polymer and its potential application to the selective extraction of adrenergic drugs from urine. Suedee R(1), Seechamnanturakit V, Canyuk B, Ovatlarnporn C, Martin GP.</span></div>
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<span style=”font-size:12px;”>A temperature sensitive dopamine-imprinted polymer was prepared in 80% aqueous methanol solution by free-radical cross-linking co-polymerisation of methacrylic acid and acrylamide at 60 degrees C in the presence of N,N-methylene-bis-acrylamide as the cross-linker and dopamine hydrochloride as template molecule.&nbsp;</span></div>
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<span style=”font-size:12px;”>2. Arch Toxicol. 1982 May;50(1):47-55. doi: 10.1007/BF00569236. Anemia and porphyria caused by N,N&#39;-methylene-bis-acrylamide (MBA) in mice and rats.Hashimoto K, Sakamoto J.</span></div>
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<span style=”font-size:12px;”>The effects of N,N&#39;-methylene-bis-acrylamide (MBA), a cross-linking agent, on blood and bone marrow after repeated oral doses, were studied in mice and rats.&nbsp;</span></div>
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<span style=”font-size:12px;”>3. Arch Toxicol. 1988 Aug;62(1):54-9. doi: 10.1007/BF00316258. Effects of N,N&#39;-methylene-bis-acrylamide (MBA) on mouse germ cells–sperm count and morphology, and testicular pathology. Sakamoto J(1), Hashimoto K.</span></div>
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<span style=”font-size:12px;”>The sperm count and morphology, and testicular histopathology were studied in mice over a period of 75 days following a single oral administration of 50, 100, and 200 mg/kg N.N&#39;-methylene-bis-acrylamide (MBA).&nbsp;</span></div>
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