NO2-SPDB-sulfo

• CAT Number: I015283
• CAS Number: 663598-89-8
• Molecular Formula: C₁₃H₁₃N₃O₉S₃
• Molecular Weight: 451.45
• Purity: ≥95%
• Target: ADC Linker

NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Reference

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.