Nonactin

• CAT Number: I010567
• CAS Number: 6833-84-7
• Molecular Formula: C40H64O12
• Molecular Weight: 736.94
• Purity: ≥95%
• Synonyms: Alternative Name: Ammonium Ionophore I
• Target: Metabolic Enzyme/Protease
• Solubility: Soluble to 10 mM in ethanol
• Storage: Desiccate at -20℃
• IUPAC Name: (1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-2,5,11,14,20,23,29,32-octamethyl-4,13,22,31,37,38,39,40-octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane-3,12,21,30-tetrone
• InChI: InChI=1S/C40H64O12/c1-21-17-29-9-13-34(49-29)26(6)38(42)46-23(3)19-31-11-15-36(51-31)28(8)40(44)48-24(4)20-32-12-16-35(52-32)27(7)39(43)47-22(2)18-30-10-14-33(50-30)25(5)37(41)45-21/h21-36H,9-20H2,1-8H3/t21-,22+,23+,24-,25-,26+,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-
• InChIKey: RMIXHJPMNBXMBU-QIIXEHPYSA-N
• SMILES: C[C@@H]1C[C@H]2CC[C@H](O2)[C@@H](C(=O)O[C@H](C[C@@H]3CC[C@@H](O3)[C@H](C(=O)O[C@@H](C[C@H]4CC[C@H](O4)[C@@H](C(=O)O[C@H](C[C@@H]5CC[C@@H](O5)[C@H](C(=O)O1)C)C)C)C)C)C)C

Nonactin（Cat No.:I010567）is a polyether antibiotic and ionophore, commonly derived from Streptomyces species. It functions by forming complexes with monovalent cations such as potassium, sodium, and ammonium, facilitating their transport across lipid membranes. This property allows Nonactin to disrupt ion gradients and cellular processes, making it useful in research related to ion transport, membrane potential, and cellular physiology. While its antimicrobial activity is well-documented, Nonactin’s primary applications are in biochemical research, especially in the study of ion channels, membranes, and the effects of ion imbalances on cellular functions.