Nonoxynol-9(Cat No.:I002888)is a nonionic surfactant commonly used as a spermicide in various contraceptive products. It works by disrupting the cell membranes of sperm cells, preventing them from fertilizing an egg. Nonoxynol-9 is found in products like vaginal creams, gels, and suppositories, as well as condoms. While it is effective at preventing pregnancy, it has been associated with an increased risk of sexually transmitted infections (STIs) in some studies, as it may cause irritation or microtears in the vaginal or rectal lining. As a result, its use has declined in favor of alternative contraceptives.