Noremopamil

For research use only. Not for therapeutic Use.

  • CAT Number: I033440
  • CAS Number: 86656-29-3
  • Molecular Formula: C22H28N2
  • Molecular Weight: 320.48
  • Purity: 98%
Inquiry Now

Noremopamil is a calcium entry blocker, also being used as the precursor for radiolabelling emopamil.


Catalog Number I033440
CAS Number 86656-29-3
Synonyms

Noremopamil; Desmethyl emopamil; Desmethyl-emopamil; Desmethylemopamil

Molecular Formula C22H28N2
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name 2-Isopropyl-2-phenyl-5-[(2-phenylethyl)amino]pentanenitrile
InChI InChI=1S/C22H28N2/c1-19(2)22(18-23,21-12-7-4-8-13-21)15-9-16-24-17-14-20-10-5-3-6-11-20/h3-8,10-13,19,24H,9,14-17H2,1-2H3
InChIKey SWJSQALWXRRRJA-UHFFFAOYSA-N
SMILES N#CC(C1=CC=CC=C1)(C(C)C)CCCNCCC2=CC=CC=C2
Reference

1: Kimura T, Yamamoto N, Suzuki Y, Kawano K, Norimine Y, Ito K, Nagato S, Iimura Y, Yonaga M. Practical synthesis of chiral emopamil left hand as a bioactive motif. J Org Chem. 2002 Aug 23;67(17):6228-31. PubMed PMID: 12182667.
2: Weber J, Bielenberg GW, Krieglstein J. Effects of phenylalkylamine calcium entry blockers on postischemic energy metabolism in the isolated perfused rat brain: stereoselective action of emopamil. Pharmacology. 1988;37(1):38-49. PubMed PMID: 2458606.

Request a Quote