Noremopamil

• CAT Number: I033440
• CAS Number: 86656-29-3
• Molecular Formula: C22H28N2
• Molecular Weight: 320.48
• Purity: 98%
• Synonyms: Noremopamil; Desmethyl emopamil; Desmethyl-emopamil; Desmethylemopamil
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2-Isopropyl-2-phenyl-5-[(2-phenylethyl)amino]pentanenitrile
• InChI: InChI=1S/C22H28N2/c1-19(2)22(18-23,21-12-7-4-8-13-21)15-9-16-24-17-14-20-10-5-3-6-11-20/h3-8,10-13,19,24H,9,14-17H2,1-2H3
• InChIKey: SWJSQALWXRRRJA-UHFFFAOYSA-N
• SMILES: N#CC(C1=CC=CC=C1)(C(C)C)CCCNCCC2=CC=CC=C2

Noremopamil(CAT: I033440) is a potent calcium channel blocker and a metabolite of verapamil. It selectively inhibits L-type calcium channels, reducing calcium influx into cells, which is critical for studying cardiovascular functions such as heart rate regulation and vascular smooth muscle relaxation. This compound is particularly valuable in cardiovascular research, supporting investigations into arrhythmias, hypertension, and ischemic heart disease. Noremopamil is an essential tool for exploring calcium signaling mechanisms and advancing therapeutic strategies targeting calcium channel modulation in cardiovascular disorders.