For research use only. Not for therapeutic Use.
Norethisterone acetate (NETA), also known as norethindrone acetate (USAN), sold under brand names including Primolut-Nor (major), Aygestin (US), Gestakadin, Milligynon, Monogest, Norlutate (US, CA), Primolut N, SH-420 (UK), Sovel, Styptin, and others, is a steroidal progestin of the 19-nortestosterone group with additional weak androgenic and estrogenic activity that is used orally as a hormonal contraceptive, in the treatment of gynecological disorders such as abnormal uterine bleeding, and as a component of hormone replacement therapy for menopause. It is the 17β-acetate ester of norethisterone, and acts as a prodrug to norethisterone in the body.
| Catalog Number | R050917 |
| CAS Number | 51-98-9 |
| Synonyms | (17α)-17-(Acetyloxy)-19-Norpregn-4-en-20-yn-3-one; 17α-Ethynyl-19-nortestosterone Acetate; 17α-Ethinyl-4-estrene-17β-ol-acetate-3-one; 19-Norethisterone Acetate; 19-Norethynyltestosterone Acetate; Aygestin; Estalis; Gynophase; Gynovlane; Milligynon; |
| Molecular Formula | C22H28O3 |
| Purity | ≥95% |
| Target | Progesterone Receptor |
| Storage | -20°C |
| InChI | 1S/C22H28O3/c1-4-22(25-14(2)23)12-10-20-19-7-5-15-13-16(24)6-8-17(15)18(19)9-11-21(20,22)3/h1,13,17-20H,5-12H2,2-3H3/t17-,18+,19+,20-,21-,22-/m0/s1 |
| InChIKey | IMONTRJLAWHYGT-ZCPXKWAGSA-N |
| SMILES | CC(=O)OC1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34)C)C#C |
| Reference | 1: Morotti M, Venturini PL, Biscaldi E, Racca A, Calanni L, Vellone VG, Stabilini |
