For research use only. Not for therapeutic Use.
Norelgestromin (Cat.No:I003940) is a metabolite of the progestin Norgestimate. It is commonly used in combination with ethinyl estradiol as a hormonal contraceptive patch. Norelgestromin functions by suppressing ovulation and altering the cervical mucus, providing effective contraception. Its transdermal delivery system offers a convenient and reliable option for birth control.
| Catalog Number | I003940 |
| CAS Number | 53016-31-2 |
| Molecular Formula | C21H29NO2 |
| Purity | ≥95% |
| Target | Drug Metabolite |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20°C |
| Reference | </br>1:A review of transdermal hormonal contraception : focus on the ethinylestradiol/norelgestromin contraceptive patch. Graziottin A.Treat Endocrinol. 2006;5(6):359-65. Review. PMID: 17107221 </br>2:Induction of androgen receptor activity by norgestimate and norelgestromin in MDA-MB 231 breast cancer cells. Prifti S, Lelle I, Strowitzki T, Rabe T.Gynecol Endocrinol. 2004 Jul;19(1):18-21. PMID: 15625768 </br>3:Ethinylestradiol + norelgestromin: new preparation. Transdermal contraception: no tangible progress. [No authors listed]Prescrire Int. 2004 Aug;13(72):123-6. PMID: 15532134 </br>4:Norelgestromin as selective estrogen enzyme modulator in human breast cancer cell lines. Effect on sulfatase activity in comparison to medroxyprogesterone acetate. Pasqualini JR, Caubel P, Friedman AJ, Philippe JC, Chetrite GS.J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):193-8. PMID: 12711003 </br>5:Transdermal contraceptive patch delivering norelgestromin and ethinyl estradiol. Effects on the lipid profile. Creasy GW, Fisher AC, Hall N, Shangold GA.J Reprod Med. 2003 Mar;48(3):179-86. PMID: 12698776 |
