For research use only. Not for therapeutic Use.
Northienamycin (Cat No.: I033470) is a bioactive natural product belonging to the thienamycin family of β-lactam antibiotics. It exhibits potent antibacterial activity by inhibiting bacterial cell wall synthesis through its interaction with penicillin-binding proteins (PBPs). As a member of the carbapenem class, Northienamycin demonstrates broad-spectrum activity against Gram-positive and Gram-negative bacteria. Its structural similarity to thienamycin suggests potential in combating resistant bacterial strains. Northienamycin is primarily studied in antibiotic research for its role in developing novel antimicrobial agents.
| CAS Number | 77550-86-8 |
| Synonyms | Northienamycin |
| Molecular Formula | C10H14N2O4S |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((2-aminoethyl)thio)-6-(hydroxymethyl)-7-oxo-, (5R-cis)- |
| InChI | InChI=1S/C10H14N2O4S/c11-1-2-17-7-3-6-5(4-13)9(14)12(6)8(7)10(15)16/h5-6,13H,1-4,11H2,(H,15,16)/t5-,6-/m1/s1 |
| InChIKey | CORBMZCTOZNVHZ-PHDIDXHHSA-N |
| SMILES | O=C(C(N12)=C(SCCN)C[C@]2([H])[C@@H](CO)C1=O)O |
| Reference | 1: Wilson KE, Kempf AJ, Liesch JM, Arison BH. Northienamycin and 8-epi-thienamycin, new carbapenems from Streptomyces cattleya. J Antibiot (Tokyo). 1983 Sep;36(9):1109-17. PubMed PMID: 6630073. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
