Norwogonin, isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (EV71) with an IC50 of 31.83 μg/ml[1]<br>Norwogonin (0.4, 2, 10, and 50 μg/mL; 48 hours) inhibits EV71 replication in Vero cells and prevents the cytotoxicity induced by EV71 infection[1].
Norwogonin (50 μg/mL; 48 hours) dramatically decreases viral VP2 protein expression[1].
Norwogonin (50 μg/mL; 48 hours) strongly decreases the expression of EV71 NCR gene at 48 h[1].
Catalog Number | I017077 |
CAS Number | 4443-09-8 |
Molecular Formula | C₁₅H₁₀O₅ |
Purity | 95% |
Reference | [1]. Choi HJ, et al. Inhibitory Effects of Norwogonin, Oroxylin A, and Mosloflavone on Enterovirus 71. Biomol Ther (Seoul). 2016 Sep 1;24(5):552-8. |