For research use only. Not for therapeutic Use.
Notexin (NpNs) is a potent neurotoxin derived from the venom of the Australian tiger snake (Notechis scutatus). It is a phospholipase A2 (PLA2) enzyme that specifically targets nerve cells, disrupting cell membranes by hydrolyzing phospholipids, leading to the release of arachidonic acid and lysophospholipids. Notexin is widely used in scientific research, particularly in studies on neuromuscular junctions, nerve degeneration, and muscle regeneration. Due to its ability to induce localized muscle damage, it serves as a model for studying muscle repair mechanisms and has been used in creating experimental models for various neurological conditions.
| Catalog Number | P000004 |
| CAS Number | 37223-96-4 |
| Molecular Formula | Np Fraction: C591H878N164O175S16 Ns Fraction: C591H878N166O175S16 |
| Purity | ≥95% |
| Solubility | Well in water and saline |
| Storage | Stable in freeze-dried state. In solution, keep at -20 °C. |
