For research use only. Not for therapeutic Use.
Novexatin（Cat No.:I008332）is a novel antifungal agent that targets dermatophytes, specifically designed for the treatment of onychomycosis and other fungal nail infections. By inhibiting key enzymes involved in fungal cell wall synthesis, it disrupts the growth and replication of the fungi. This compound has shown efficacy in clinical trials, reducing fungal load and promoting nail health. Novexatin offers an innovative, topical treatment option, with a formulation designed to penetrate the nail to deliver active ingredients directly to the infection site, ensuring effective fungal eradication. Ideal for use in persistent and difficult-to-treat fungal infections.
| Catalog Number | I008332 |
| CAS Number | 942577-31-3 |
| Synonyms | NP-213; NP213; NP 213; Novexatin;2-[3-[(2S,5S,8S,11S,14S,17S,20S)-5,8,11,14,17,20-hexakis[3-(diaminomethylideneamino)propyl]-3,6,9,12,15,18,21-heptaoxo-1,4,7,10,13,16,19-heptazacyclohenicos-2-yl]propyl]guanidine |
| Molecular Formula | C42H84N28O7 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4 °C for short term, or -20 °C for long term |
| IUPAC Name | 2-[3-[(2S,5S,8S,11S,14S,17S,20S)-5,8,11,14,17,20-hexakis[3-(diaminomethylideneamino)propyl]-3,6,9,12,15,18,21-heptaoxo-1,4,7,10,13,16,19-heptazacyclohenicos-2-yl]propyl]guanidine |
| InChI | InChI=1S/C42H84N28O7/c43-36(44)57-15-1-8-22-29(71)65-24(10-3-17-59-38(47)48)31(73)67-26(12-5-19-61-40(51)52)33(75)69-28(14-7-21-63-42(55)56)35(77)70-27(13-6-20-62-41(53)54)34(76)68-25(11-4-18-60-39(49)50)32(74)66-23(30(72)64-22)9-2-16-58-37(45)46/h22-28H,1-21H2,(H,64,72)(H,65,71)(H,66,74)(H,67,73)(H,68,76)(H,69,75)(H,70,77)(H4,43,44,57)(H4,45,46,58)(H4,47,48,59)(H4,49,50,60)(H4,51,52,61)(H4,53,54,62)(H4,55,56,63)/t22-,23-,24-,25-,26-,27-,28-/m0/s1 |
| InChIKey | NVZLKNHDHPPJHL-RMIXPHLWSA-N |
| SMILES | C(C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCN=C(N)N)CCCN=C(N)N)CCCN=C(N)N)CCCN=C(N)N)CCCN=C(N)N)CCCN=C(N)N)CN=C(N)N |
