For research use only. Not for therapeutic Use.
NPPM 6748-481 is a selective inhibitor of the yeast phosphatidylinositol transfer protein (PITP) Sec14[1].
| Catalog Number | R028720 |
| CAS Number | 432020-20-7 |
| Synonyms | (4-chloro-3-nitrophenyl)-[4-(2-fluorophenyl)piperazin-1-yl]methanone |
| Molecular Formula | C17H15ClFN3O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C17H15ClFN3O3/c18-13-6-5-12(11-16(13)22(24)25)17(23)21-9-7-20(8-10-21)15-4-2-1-3-14(15)19/h1-6,11H,7-10H2 |
| InChIKey | LSPJXCGEFJDMHA-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1C2=CC=CC=C2F)C(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-] |
| Reference | [1]. Nile, Aaron H.; Tripathi, Ashutosh; Yuan, Peihua; et al. PITPs as targets for selectively interfering with phosphoinositide signaling in cells. Nature Chemical Biology (2014), 10(1), 76-84. |
