NPPM 6748-481

• CAT Number: R028720
• CAS Number: 432020-20-7
• Molecular Formula: C17H15ClFN3O3
• Molecular Weight: 363.77
• Purity: ≥95%
• Synonyms: (4-chloro-3-nitrophenyl)-[4-(2-fluorophenyl)piperazin-1-yl]methanone
• InChI: InChI=1S/C17H15ClFN3O3/c18-13-6-5-12(11-16(13)22(24)25)17(23)21-9-7-20(8-10-21)15-4-2-1-3-14(15)19/h1-6,11H,7-10H2
• InChIKey: LSPJXCGEFJDMHA-UHFFFAOYSA-N
• SMILES: C1CN(CCN1C2=CC=CC=C2F)C(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]

NPPM 6748-481 is a selective inhibitor of the yeast phosphatidylinositol transfer protein (PITP) Sec14[1].

Reference

[1]. Nile, Aaron H.; Tripathi, Ashutosh; Yuan, Peihua; et al. PITPs as targets for selectively interfering with phosphoinositide signaling in cells. Nature Chemical Biology (2014), 10(1), 76-84.
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