Nrf2-Activator-12G

• CAT Number: I033535
• CAS Number: 1554271-18-9
• Molecular Formula: C15H13ClO3S
• Molecular Weight: 308.78
• Purity: ≥95%
• Synonyms: 1-chloro-2-[(E)-2-(2-methoxyphenyl)sulfonylethenyl]benzene
• InChI: InChI=1S/C15H13ClO3S/c1-19-14-8-4-5-9-15(14)20(17,18)11-10-12-6-2-3-7-13(12)16/h2-11H,1H3/b11-10+
• InChIKey: KVDYSDOWSIXKPB-ZHACJKMWSA-N
• SMILES: COC1=CC=CC=C1S(=O)(=O)C=CC2=CC=CC=C2Cl

Nrf2-Activator-12G (compd 12g) is an activator of Nrf2. Nrf2-Activator-12G induces the expression of nrf2-dependentantioxidant enzymes at both mRNA and protein levels in DAergic neuronal cell. Nrf2-Activator-12G can used in study Parkinson’s Disease[1].

Reference

[1]. Woo SY, et al. Discovery of vinyl sulfones as a novel class of neuroprotective agents toward Parkinson’s disease therapy. J Med Chem. 2014 Feb 27;57(4):1473-87.
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