For research use only. Not for therapeutic Use.
NS-0011 is an inhibitor of CDK5 translocation which increases CDK5 accumulation in the nucleus, suppressing both cancer cell proliferation and xenograft tumorigenesis.
| Catalog Number | I033537 |
| CAS Number | 1076234-33-7 |
| Synonyms | NS-0011; NS0011; NS 0011; S00109 |
| Molecular Formula | C12H9ClF3N3O2 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 1-[[6-Chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-3,4-dimethyl-1H-pyrrole-2,5-dione |
| InChI | InChI=1S/C12H9ClF3N3O2/c1-5-6(2)11(21)19(10(5)20)18-8-4-3-7(9(13)17-8)12(14,15)16/h3-4H,1-2H3,(H,17,18) |
| InChIKey | VBIXDLJJOWRQKF-UHFFFAOYSA-N |
| SMILES | O=C(C(C)=C1C)N(NC2=NC(Cl)=C(C(F)(F)F)C=C2)C1=O |
