For research use only. Not for therapeutic Use.
NS9283 is a positive positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors. NS9283 can be used in a series of neurological conditions such as attention deficit hyperactivity disorder (ADHD), schizophrenia, Parkinson’s disease and Alzheimer’s disease[1].
| Catalog Number | R014426 |
| CAS Number | 913830-15-6 |
| Synonyms | 3-(3-pyridin-3-yl-1,2,4-oxadiazol-5-yl)benzonitrile |
| Molecular Formula | C14H8N4O |
| Purity | ≥95% |
| InChI | InChI=1S/C14H8N4O/c15-8-10-3-1-4-11(7-10)14-17-13(18-19-14)12-5-2-6-16-9-12/h1-7,9H |
| InChIKey | HGFXDSQLRSWUBO-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC(=C1)C2=NC(=NO2)C3=CN=CC=C3)C#N |
| Reference | [1]. M Grupe, et al. Unravelling the mechanism of action of NS9283, a positive allosteric modulator of (α4)3(β2) 2nicotinic ACh receptors. Br J Pharmacol. 2013 Apr;168(8):2000-10. |
