NSC-207895

• CAT Number: I002367
• CAS Number: 58131-57-0
• Molecular Formula: C11H13N5O4
• Molecular Weight: 279.25
• Purity: ≥95%
• Synonyms: 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium
• Target: MDM-2/p53
• Solubility: Limited solubility
• Storage: Store at -20°C
• InChI: InChI=1S/C11H13N5O4/c1-13-4-6-14(7-5-13)9-3-2-8(15(17)18)10-11(9)16(19)20-12-10/h2-3H,4-7H2,1H3
• InChIKey: MWFZDJLPWDCQIL-UHFFFAOYSA-N
• SMILES: CN1CCN(CC1)C2=CC=C(C3=NO[N+](=C23)[O-])[N+](=O)[O-]

NSC-207895（Cat No.:I002367） has been shown to inhibit the MDMX protein with an IC50 of 2.5 μM. This inhibition promotes p53 stabilization/activation and DNA damage while also regulating the MDM2 E3 ligase. NSC-207895’s ability to modulate these key proteins involved in cancer cell survival and proliferation suggests its potential as an anti-cancer agent. However, further studies are required to determine its effectiveness and safety for clinical use.