NSC-41589

• CAT Number: I004380
• CAS Number: 6310-41-4
• Molecular Formula: C9H11NOS
• Molecular Weight: 181.25
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• InChI: InChI=1S/C9H11NOS/c1-7(11)10-8-5-3-4-6-9(8)12-2/h3-6H,1-2H3,(H,10,11)
• InChIKey: AMWFIKFWXRBICX-UHFFFAOYSA-N
• SMILES: CSC1=CC=CC=C1NC(C)=O

NSC-41589(CAT: I004380), also known as Flavopiridol, is a synthetic flavone derivative that functions as a potent and broad-spectrum cyclin-dependent kinase (CDK) inhibitor. Flavopiridol exhibits its inhibitory activity by disrupting cell cycle progression through the inhibition of CDKs, particularly CDK1, CDK2, CDK4, and CDK9. This disruption leads to the suppression of RNA synthesis and cell proliferation. Flavopiridol has shown promise in preclinical studies and clinical trials for the treatment of various types of cancer, and its multifaceted mechanism of action makes it a valuable candidate for further investigation in cancer therapy.