For research use only. Not for therapeutic Use.
NSC 48160 inhibits the growth of the pancreatic cancer cells with IC50s of 84.3 μM for CPFAC-1 and 94.5 μM for BxPC-3. NSC 48160 also induces pancreatic cancer cell apoptosis. NSC 48160 can improve metabolic syndromes, such as NASH, obesity and lipid metabolism disorders[1][2].
| Catalog Number | I012184 |
| CAS Number | 6640-90-0 |
| Synonyms | 4-tert-butyl-2-[(cyclohexylamino)methyl]-6-methylphenol |
| Molecular Formula | C18H29NO |
| Purity | ≥95% |
| InChI | InChI=1S/C18H29NO/c1-13-10-15(18(2,3)4)11-14(17(13)20)12-19-16-8-6-5-7-9-16/h10-11,16,19-20H,5-9,12H2,1-4H3 |
| InChIKey | DVMJYVSFWOSELO-UHFFFAOYSA-N |
| SMILES | CC1=CC(=CC(=C1O)CNC2CCCCC2)C(C)(C)C |
| Reference | [1]. Li D, et al. A small-molecule induces apoptosis and suppresses metastasis in pancreatic cancer cells. Eur J Pharm Sci. 2013 Mar 12;48(4-5):658-67. [2]. Liu zuijia, et al. Application of small molecule compound NSC48160 in preparation of medicine for treating non-alcoholic fatty liver disease. Patent. CN115869292 |
