NSC 689534

• CAT Number: I040169
• CAS Number: 907958-80-9
• Molecular Formula: C19H18N6S
• Molecular Weight: 362.45
• Purity: ≥95%
• Synonyms: 1,1-bis(pyridin-2-ylmethyl)-3-[(E)-pyridin-2-ylmethylideneamino]thiourea
• InChI: InChI=1S/C19H18N6S/c26-19(24-23-13-16-7-1-4-10-20-16)25(14-17-8-2-5-11-21-17)15-18-9-3-6-12-22-18/h1-13H,14-15H2,(H,24,26)/b23-13+
• InChIKey: AEEZWHXVVXFVAD-YDZHTSKRSA-N
• SMILES: C1=CC=NC(=C1)CN(CC2=CC=CC=N2)C(=S)NN=CC3=CC=CC=N3

NSC 689534 (Cat No.: I040169) is a synthetic small molecule identified through screening programs for its potential anticancer activity. It has shown promise in preclinical studies by targeting specific molecular pathways involved in tumor growth and survival. The compound is believed to modulate key enzymes or proteins that regulate cell cycle progression and apoptosis, making it a potential therapeutic agent for various cancers. Ongoing research is focused on elucidating its mechanism of action and evaluating its efficacy in clinical trials for cancer treatment.

Reference

[1]. Chad N Hancock, et al. A copper chelate of thiosemicarbazone NSC 689534 induces oxidative/ER stress and inhibits tumor growth in vitro and in vivo. Free Radic Biol Med. 2011 Jan 1;50(1):110-21.
[Content Brief]

[2]. Hancock CN, et al. A copper chelate of thiosemicarbazone NSC 689534 induces oxidative/ER stress and inhibits tumor growth in vitro and in vivo. Free Radic Biol Med. 2011 Jan 1;50(1):110-21.
[Content Brief]