NSC2805

For research use only. Not for therapeutic Use.

  • CAT Number: I033586
  • CAS Number: 4371-34-0
  • Molecular Formula: C14H14O4
  • Molecular Weight: 246.26
  • Purity: ≥95%
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​NSC2805(Cat No.:I033586)is a potent inhibitor of the WWP2 ubiquitin ligase, exhibiting an IC₅₀ of 0.38 μM. WWP2, an E3 ubiquitin ligase, plays a crucial role in the ubiquitination and subsequent degradation of target proteins, including the tumor suppressor PTEN. By inhibiting WWP2, NSC2805 effectively reduces PTEN ubiquitination, leading to its stabilization and potential tumor-suppressive effects. This mechanism positions NSC2805 as a valuable compound for cancer research, offering insights into therapeutic strategies that modulate ubiquitin ligase activity to restore tumor suppressor functions. ​


CAS Number 4371-34-0
Synonyms

2-(2,5-dihydroxy-4-methylphenyl)-5-methylbenzene-1,4-diol

Molecular Formula C14H14O4
Purity ≥95%
IUPAC Name 2-(2,5-dihydroxy-4-methylphenyl)-5-methylbenzene-1,4-diol
InChI InChI=1S/C14H14O4/c1-7-3-13(17)9(5-11(7)15)10-6-12(16)8(2)4-14(10)18/h3-6,15-18H,1-2H3
InChIKey DSVRCBOSZSZMRX-UHFFFAOYSA-N
SMILES CC1=CC(=C(C=C1O)C2=C(C=C(C(=C2)O)C)O)O

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