NSC319726

For research use only. Not for therapeutic Use.

  • CAT Number: I004668
  • CAS Number: 71555-25-4
  • Molecular Formula: C11H14N4S
  • Molecular Weight: 234.32
  • Purity: ≥95%
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NSC 319726 (Cat No.:I004668) is a small molecule that has been investigated for its potential anticancer properties. It functions as an inhibitor of specific signaling pathways involved in cell survival and proliferation, particularly in cancer cells. NSC319726 has shown promise in preclinical studies for its ability to suppress tumor growth, including in certain types of leukemia. Its exact mechanism of action is still under investigation, but it may target key proteins involved in cancer cell metabolism and apoptosis, offering potential for therapeutic use.


Catalog Number I004668
CAS Number 71555-25-4
Synonyms

N-[(Z)-1-pyridin-2-ylethylideneamino]azetidine-1-carbothioamide

Molecular Formula C11H14N4S
Purity ≥95%
Target MDM-2/p53
Solubility DMSO: ≤ 27.5 mg/mL
Storage Store at -20°C
IC50 8 nM
IUPAC Name N-[(E)-1-pyridin-2-ylethylideneamino]azetidine-1-carbothioamide
InChI InChI=1S/C11H14N4S/c1-9(10-5-2-3-6-12-10)13-14-11(16)15-7-4-8-15/h2-3,5-6H,4,7-8H2,1H3,(H,14,16)/b13-9+
InChIKey XDHBUMNIQRLHGO-UKTHLTGXSA-N
SMILES CC(=NNC(=S)N1CCC1)C2=CC=CC=N2
Reference

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<br>[1]. Yu X, et al. Allele-specific p53 mutant reactivation. Cancer Cell. 2012 May 15;21(5):614-25.
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