NSC351149

• CAT Number: I013332
• CAS Number: 53597-28-7
• Molecular Formula: C₂₆H₂₀Cl₅FN₂O₂
• Molecular Weight: 588.71
• Purity: ≥95%
• Target: Fungal
• Solubility: DMSO
• Storage: Store at -20°C
• IUPAC Name: 2-[3-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazol-1-ium-1-yl]-1-(4-fluorophenyl)ethanone;chloride
• InChI: InChI=1S/C26H20Cl4FN2O2.ClH/c27-19-4-1-18(23(29)11-19)15-35-26(22-8-5-20(28)12-24(22)30)14-33-10-9-32(16-33)13-25(34)17-2-6-21(31)7-3-17;/h1-12,16,26H,13-15H2;1H/q+1;/p-1
• InChIKey: JWPMAPBNVNRWBX-UHFFFAOYSA-M
• SMILES: C1=CC(=CC=C1C(=O)C[N+]2=CN(C=C2)CC(C3=C(C=C(C=C3)Cl)Cl)OCC4=C(C=C(C=C4)Cl)Cl)F.[Cl-]

NSC351149（Cat No.:I013332）is a synthetic compound known for its potential in cancer therapy due to its ability to inhibit protein synthesis. It functions as an inhibitor of eukaryotic translation, disrupting the process of protein translation, which is essential for cell growth and survival. NSC351149 has shown promise in preclinical studies for targeting cancer cells by hindering their protein synthesis machinery, ultimately leading to reduced tumor cell proliferation. Its mechanism of action makes it a valuable candidate for further investigation in the development of targeted cancer therapies.

Reference

[1]. Andrew Redington. Methods relating to the use of remote ischemic conditioning. US 20160038737 A1.