NSI-189 phosphate

• CAT Number: I010177
• CAS Number: 1270138-41-4
• Molecular Formula: C22H33N4O5P
• Molecular Weight: 464.50
• Purity: ≥95%
• Synonyms: Methanone, [2-​[(3-​methylbutyl)​amino]​-​3-​pyridinyl]​[4-​(phenylmethyl)​-​1-​piperazinyl]​-​, phosphate (1:1)
• Storage: Store at -20°C
• Related CAS: 1270138-40-3(free base)
• IUPAC Name: (4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone;phosphoric acid
• InChI: InChI=1S/C22H30N4O.H3O4P/c1-18(2)10-12-24-21-20(9-6-11-23-21)22(27)26-15-13-25(14-16-26)17-19-7-4-3-5-8-19;1-5(2,3)4/h3-9,11,18H,10,12-17H2,1-2H3,(H,23,24);(H3,1,2,3,4)
• InChIKey: LWHMGALTTIYPJU-UHFFFAOYSA-N
• SMILES: CC(C)CCNC1=C(C=CC=N1)C(=O)N2CCN(CC2)CC3=CC=CC=C3.OP(=O)(O)O

NSI-189 phosphate（Cat No.:I010177） is a novel compound primarily investigated for its potential therapeutic effects on conditions like major depressive disorder and other neurological disorders. It is a small molecule that stimulates the neurogenesis of human hippocampus-derived neural stem cells in vitro and in vivo. By potentially increasing brain plasticity and enhancing neurogenesis, NSI-189 phosphate aims to address the underlying causes of depression rather than merely treating its symptoms. It has been in clinical trials, exploring its efficacy and safety in improving cognitive and behavioral symptoms associated with depression and other neurodegenerative diseases.