NSP-DMAE-NHS

• CAT Number: M144094
• CAS Number: 194357-64-7
• Molecular Formula: C30H26N2O9S
• Molecular Weight: 590.603
• Purity: ≥95%
• Synonyms: 9-[[4-[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]-2,6-dimethylphenoxy]carbonyl]-10-(3-sulfopropyl)acridinium Inner Salt; 2’,6’-Dimethyl-4’-(N-succinimidyloxycarbonyl) phenyl-10-sulfopropylacridinium-9-carboxylate
• Storage: Store at 0-8°C
• IUPAC Name: 3-[9-[4-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-2,6-dimethylphenoxy]carbonylacridin-10-ium-10-yl]propane-1-sulfonate
• InChI: InChI=1S/C30H26N2O9S/c1-18-16-20(29(35)41-32-25(33)12-13-26(32)34)17-19(2)28(18)40-30(36)27-21-8-3-5-10-23(21)31(14-7-15-42(37,38)39)24-11-6-4-9-22(24)27/h3-6,8-11,16-17H,7,12-15H2,1-2H3
• InChIKey: AAYSIOJYGRABGS-UHFFFAOYSA-N
• SMILES: CC1=CC(=CC(=C1OC(=O)C2=C3C=CC=CC3=[N+](C4=CC=CC=C42)CCCS(=O)(=O)[O-])C)C(=O)ON5C(=O)CCC5=O

NSP-DMAE-NHS (CAT: M144094) is a new kind of highly efficient luminescence reagent containing N-sulfopropyl groups. It is useful in the clinical diagnostic industry especially in automated immunochemical analyzers. It is considered a useful research tool for the investigation of protein-carbohydrate interactions to characterize the binding affinity between specific carbohydrates and their binding protein. 

Reference

1. Bolt, H., et al., Toxicol. Lett., 151, 251 (2004)
2. Malhotra, S., et al., Bioorg. Med. Chem. Lett., 20, 581 (2010)
3. Natrajan, A., et al., Anal. Biochem., 406, 204 (2010)
4.Wang, Linyu, et al. "Novel Competitive Chemiluminescence DNA Assay Based on Fe 3 O 4@ SiO 2@ Au-Functionalized Magnetic Nanoparticles for Sensitive Detection of p53 Tumor Suppressor Gene." Applied biochemistry and biotechnology 187.1 (2019): 152-162.