Nucleocidin

• CAT Number: R042279
• CAS Number: 24751-69-7
• Molecular Formula: C10H13FN6O6S
• Molecular Weight: 364.31
• Purity: ≥95%
• Synonyms: 4’-C-Fluoroadenosine 5’-Sulfamate; 4’-Fluoro-5’-O-sulfamoyladenosine; NSC 521007
• Storage: -20°C
• IUPAC Name: [(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-2-fluoro-3,4-dihydroxyoxolan-2-yl]methyl sulfamate
• InChI: InChI=1S/C10H13FN6O6S/c11-10(1-22-24(13,20)21)6(19)5(18)9(23-10)17-3-16-4-7(12)14-2-15-8(4)17/h2-3,5-6,9,18-19H,1H2,(H2,12,14,15)(H2,13,20,21)/t5-,6+,9-,10-/m1/s1
• InChIKey: LTBCQBSAWAZBDF-MLTZYSBQSA-N
• SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@](O3)(COS(=O)(=O)N)F)O)O)N

Nucleocidin（Cat No.:R042279）is a potent antibiotic belonging to the nucleoside family, known for its unique fluorine atom incorporated into its molecular structure. It inhibits protein synthesis by targeting and interfering with bacterial tRNA synthetase, an enzyme essential for amino acid attachment and protein assembly. This disruption leads to bacterial cell death, making nucleocidin effective against a range of pathogens, including certain parasitic infections. Its distinct mechanism and fluorine-based structure make nucleocidin a valuable compound in antimicrobial research, offering insights into novel antibiotic strategies and potential treatments for resistant infections.