Nucleoside-Analog-2

• CAT Number: I005276
• CAS Number: 876708-01-9
• Molecular Formula: C9H11N5O6
• Molecular Weight: 285.21
• Purity: ≥95%
• Target: Anti-infection
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: 1-[(2R,3S,4S,5R)-5-azido-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
• InChI: InChI=1S/C9H11N5O6/c10-13-12-9(3-15)6(18)5(17)7(20-9)14-2-1-4(16)11-8(14)19/h1-2,5-7,15,17-18H,3H2,(H,11,16,19)/t5-,6-,7+,9+/m0/s1
• InChIKey: FHPJZSIIXUQGQE-XZMZPDFPSA-N
• SMILES: C1=CN(C(=O)NC1=O)[C@H]2[C@H]([C@@H]([C@](O2)(CO)N=[N+]=[N-])O)O

Nucleoside-Analog-2（Cat No.:I005276）is a synthetic compound designed to mimic natural nucleosides, playing a crucial role in the study of nucleic acid metabolism and potential therapeutic applications. This analog can interfere with DNA and RNA synthesis, making it a candidate for antiviral and anticancer research. By incorporating structural modifications, Nucleoside-Analog-2 may exhibit enhanced stability and bioactivity compared to its natural counterparts. Ongoing research aims to evaluate its pharmacological properties, mechanisms of action, and efficacy in disrupting viral replication or tumor cell proliferation, highlighting its potential as a novel therapeutic agent.

Reference

[1]. Smith DB, et al. The design, synthesis, and antiviral activity of 4/’-azidocytidine analogues against hepatitis C virus replication: the discovery of 4/’-azidoarabinocytidine. J Med Chem. 2009 Jan 8;52(1):219-23.
[2]. Smith DB, et al. The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4/’-azidocytidine against hepatitis C virus replication: the discovery of 4/’-azido-2/’-deoxy-2/’-fluorocytidine and 4/’-azido-2/’-dideoxy-2/’,2/’-difluorocytidine. J Med Chem. 2009 May 14;52(9):2971-8.