Nurr1 agonist 4

• CAT Number: I041093
• CAS Number: 87645-58-7
• Molecular Formula: C12H10O4
• Molecular Weight: 218.21
• Purity: ≥95%
• Synonyms: 5-(4-methoxyphenyl)furan-3-carboxylic acid
• InChI: InChI=1S/C12H10O4/c1-15-10-4-2-8(3-5-10)11-6-9(7-16-11)12(13)14/h2-7H,1H3,(H,13,14)
• InChIKey: KGKSJJKOSONHJU-UHFFFAOYSA-N
• SMILES: COC1=CC=C(C=C1)C2=CC(=CO2)C(=O)O

Nurr1 agonist 4 (compound 8) is a high-affinity Nurr1 agonist with EC50 of 2.1 μM[1].

Reference

[1]. Marco Ballarotto, et al. De Novo Design of Nurr1 Agonists via Fragment-Augmented Generative Deep Learning in Low-Data Regime. J Med Chem. 2023 Jun 22;66(12):8170-8177.
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