For research use only. Not for therapeutic Use.
Nutlin carboxylic acid (Cat.No:I018612) is a derivative of Nutlin, a potent inhibitor of the MDM2-p53 interaction. It functions by disrupting the interaction between MDM2 and p53, leading to p53 activation and subsequent apoptosis of cancer cells. Nutlin carboxylic acid holds potential as an anticancer agent and is actively being investigated in preclinical studies.
Catalog Number | I018612 |
CAS Number | 2249750-27-2 |
Molecular Formula | C₃₂H₃₂Cl₂N₄O₆ |
Purity | ≥95% |
Target | Ligands for E3 Ligase |
Reference | [1]. Dimer amide micromolecule PROTACs for inducing MDM2 to self-degrade E3 ubiquitin ligase. CN108610333A. |