NVP 231

• CAT Number: I003329
• CAS Number: 362003-83-6
• Molecular Formula: C25H25N3O2S
• Molecular Weight: 431.55
• Purity: ≥95%
• Synonyms: N-(2-benzamido-1,3-benzothiazol-6-yl)adamantane-1-carboxamide
• Target: Apoptosis
• Solubility: DMSO: ≥ 41 mg/mL
• Storage: Store at +4°C
• IC50: 12±2 nM
• InChI: InChI=1S/C25H25N3O2S/c29-22(18-4-2-1-3-5-18)28-24-27-20-7-6-19(11-21(20)31-24)26-23(30)25-12-15-8-16(13-25)10-17(9-15)14-25/h1-7,11,15-17H,8-10,12-14H2,(H,26,30)(H,27,28,29)
• InChIKey: MVSSJPGNLQPWSW-FGUCWDTJSA-N
• SMILES: O=C(C1(C[C@@H](C2)C3)C[C@H]3CC2C1)NC4=CC(SC(NC(C5=CC=CC=C5)=O)=N6)=C6C=C4

NVP 231（Cat No.:I003329）is a newly developed inhibitor of Ceramide Kinase (CerK) that shows high potency against the enzyme in vitro assays, with an IC50 value of 12 nM. CerK is a key regulator of ceramide metabolism and has been implicated in various cellular processes such as cell growth and apoptosis. NVP 231’s inhibition of CerK may have therapeutic potential for diseases associated with altered ceramide metabolism.