For research use only. Not for therapeutic Use.
NVP-VID-400(Cat No.:I008388)is a selective inhibitor of mitotic checkpoint kinase Mps1 (Monopolar spindle 1), a critical enzyme involved in spindle assembly and chromosome alignment during cell division. By targeting Mps1, NVP-VID-400 disrupts proper mitotic progression, leading to mitotic arrest and apoptosis in rapidly dividing cancer cells. Its specificity for Mps1 makes it a valuable tool in cancer research, especially in studying tumor types reliant on enhanced mitotic activity. NVP-VID-400 holds potential for development in targeted cancer therapies, focusing on inhibiting cancer cell proliferation through mitotic checkpoint disruption.
Catalog Number | I008388 |
CAS Number | 174262-13-6 |
Synonyms | NVP-VID-400; NVP-VID 400; NVP-VID400; SDZ285428; SDZ 285428; SDZ-285428; SDZ285-428; SDZ 285-428; SDZ-285-428.;N-(2-(1H-imidazol-1-yl)-2-phenylethyl)-4/’-chloro-[1,1/’-biphenyl]-4-carboxamide |
Molecular Formula | C24H20ClN3O |
Purity | ≥95% |
Target | Anti-infection |
Solubility | Soluble in DMSO |
Storage | -20°C |
IUPAC Name | 4-(4-chlorophenyl)-N-(2-imidazol-1-yl-2-phenylethyl)benzamide |
InChI | InChI=1S/C24H20ClN3O/c25-22-12-10-19(11-13-22)18-6-8-21(9-7-18)24(29)27-16-23(28-15-14-26-17-28)20-4-2-1-3-5-20/h1-15,17,23H,16H2,(H,27,29) |
InChIKey | FHHNSSGZEIVGMS-UHFFFAOYSA-N |
SMILES | C1=CC=C(C=C1)C(CNC(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)Cl)N4C=CN=C4 |